SeguraBlawg's Psoriasis vs. Dermatophytosis Blawg

Moxifloxacin in respiratory tract infections. [Expert Opin Pharmacother. 2005] - PubMed result

2010-07-20T01:44:00.000-07:00

Moxifloxacin in respiratory tract infections. [Expert Opin Pharmacother. 2005] - PubMed result

Moxifloxacin in the management of exacerbations of chronic bronchitis and COPD

2010-07-20T01:42:00.000-07:00

Moxifloxacin in the management of exacerbations of chronic bronchitis and COPD

The safety and efficacy of short course (5-day) mo... [Respir Med. 2000] - PubMed result

2010-07-20T01:30:00.000-07:00

The safety and efficacy of short course (5-day) mo... [Respir Med. 2000] - PubMed result

Short-course moxifloxacin therapy for treatment of... [Respir Med. 2000] - PubMed result

2010-07-20T01:28:00.000-07:00

Short-course moxifloxacin therapy for treatment of acute bacterial exacerbations of chronic bronchitis. The Bronchitis Study Group.[Respir Med. 2000] - PubMed result

Moxifloxacin five-day therapy versus placebo in ac... [Laryngoscope. 2010] - PubMed result

2010-07-20T01:26:00.000-07:00

Moxifloxacin five-day therapy versus placebo in ac... [Laryngoscope. 2010] - PubMed result

Comparative efficacies of amoxicillin, clindamycin... [Antimicrob Agents Chemother. 2006] - PubMed result

2010-07-20T01:23:00.000-07:00

Comparative efficacies of amoxicillin, clindamycin... [Antimicrob Agents Chemother. 2006] - PubMed result

In vitro activity of moxifloxacin compared to othe... [Oral Microbiol Immunol. 2004] - PubMed result

2010-07-20T01:22:00.000-07:00

In vitro activity of moxifloxacin compared to othe... [Oral Microbiol Immunol. 2004] - PubMed result

Evidence for the involvement of bacterial superantigens in psoriasis ... [FEMS Microbiol Lett. 2000] - PubMed result

2010-07-20T00:08:00.000-07:00

Evidence for the involvement of bacterial superantigens in psoriasis, atopic dermatitis, and Kawasaki syndrome.[FEMS Microbiol Lett. 2000] - PubMed result

Bacterial superantigens and inflammatory skin disease [Clin Exp Dermatol. 2000] - PubMed result

2010-07-20T00:06:00.000-07:00

Bacterial superantigens and inflammatory skin disease [Clin Exp Dermatol. 2000] - PubMed result

Hyporesponsiveness of peripheral blood lymphocytes... [Arch Dermatol Res. 1999 Jul-Aug] - PubMed result

2010-07-20T00:00:00.000-07:00

Hyporesponsiveness of peripheral blood lymphocytes to streptococcal superantigens in patients with guttate psoriasis: evidence for systemic stimulation of T cells with superantigens released from focally infecting Streptococcus pyogenes.[Arch Dermatol Res. 1999 Jul-Aug] - PubMed result

Peripheral blood lymphocytes from psoriatic patien... [Br J Dermatol. 1998] - PubMed result

2010-07-19T23:58:00.000-07:00

Peripheral blood lymphocytes from psoriatic patients are hyporesponsive to beta-streptococcal superantigens.[Br J Dermatol. 1998] - PubMed result

Psoriasis: a T-cell-mediated autoimmune disease in... [Immunol Today. 1995] - PubMed result

2010-07-19T23:54:00.000-07:00

Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens?[Immunol Today. 1995] - PubMed result

Is psoriasis induced by streptococcal superantigens and T cells that cross-react with keratin?

2010-07-19T23:52:00.000-07:00

Is psoriasis induced by streptococcal superantigens and maintained by M-protein-specific T cells that cross-react with keratin? [Clin Exp Immunol. 1997] - PubMed result

Psoriasis--as an autoimmune disease caused by molecular mimicry [Trends Immunol. 2009] - PubMed result

2010-07-19T23:49:00.000-07:00

Psoriasis--as an autoimmune disease caused by molecular mimicry [Trends Immunol. 2009] - PubMed result

Is psoriasis induced by streptococcal superantigens and maintained by M-protein-specific T cells that cross-react with keratin? Clin Exp Immunol.1997

2010-07-19T23:45:00.000-07:00

Is psoriasis induced by streptococcal superantigens and maintained by M-protein-specific T cells that cross-react with keratin? [Clin Exp Immunol. 1997] - PubMed result

Psoriasis vulgaris--a sterile antibacterial skin r... [Clin Exp Dermatol. 2001] - PubMed result

2010-07-19T23:07:00.000-07:00

Psoriasis vulgaris--a sterile antibacterial skin reaction mediated by cross-reactive T cells? An immunological view of the pathophysiology of psoriasis. - PubMed result

The Whitfield Tradition of Therapy

2010-07-19T22:59:00.000-07:00

The Whitfield Tradition of Therapy

Recognition of Streptococcus pyogenes and skin aut... [Arch Med Res. 1998] - PubMed result

2010-07-19T22:57:00.000-07:00

Recognition of Streptococcus pyogenes and skin aut... [Arch Med Res. 1998] - PubMed result

Strep Throat, Antibiotics & Psoriasis - iVillage Your Total Health

2010-01-27T23:11:00.000-08:00

Strep Throat, Antibiotics & Psoriasis - iVillage Your Total Health

Multiple factors can worsen psoriasis or cause the guttate form. Many drugs have been implicated, but antibiotics would be unlikely to initiate the illness. One intriguing cause of guttate psoriasis or psoriatic flares is infection with Streptococcal bacteria, including strep throat or a strep skin infection. Guttate psoriasis may happen because strep bacteria can make a type of toxin known as a "superantigen." Superantigens are capable of activating many different aspects of the body's disease-fighting immune system, with widespread effects. (This mechanism is responsible for the toxic-shock syndrome associated with tampon use.) In the case of psoriasis, the strep toxin may activate immune cells in the skin, resulting in the multiple psoriasis skin lesions.

The role of streptococcal infection in the initiat... [Arch Dermatol. 1992] - PubMed result

2010-01-23T23:55:00.000-08:00

The role of streptococcal infection in the initiat... [Arch Dermatol. 1992] - PubMed result

AccessMedicine | Streptococcal Skin Infections

2010-01-23T23:41:00.000-08:00

AccessMedicine | Streptococcal Skin Infections

Group A streptococci are usually spread by transfer of organisms from an infected person or carrier through close personal contact. The major source of such spread is from patients with infections in the upper respiratory tract. Approximately 10 percent of the normal population carry group A streptococcus asymptomatically—a higher percentage of adults than of children in the oropharynx and less commonly in the nares and anus. Although the carriage rate of group A streptococcus on normal skin is less than 1 percent, a variety of skin lesions and puerperal sepsis may also be the source of intrahospital spread of infection. Group A streptococci introduced into the operating room in the form of a minor skin infection, or even through perianal carriage by a surgeon or anesthetist, may be responsible for an epidemic of streptococcal wound infections.Impetigo caused by group A streptococcus is a highly communicable infection and occurs predominantly in preschool-aged children (usually before the age of 2 years except in highly endemic areas). It is more common in warmer, more humid climates than in temperate zones. Its peak seasonal incidence is in the later summer and early fall.

Perianal Streptococcal Dermatitis Associated With Guttate Psoriasis and/or Balanoposthitis: A Study of Five Cases. Annalisa Patrizi. 2008; Pediatric Dermatology - Wiley InterScience

2010-01-23T23:31:00.000-08:00

Perianal Streptococcal Dermatitis Associated With Guttate Psoriasis and/or Balanoposthitis: A Study of Five Cases. Annalisa Patrizi. 2008; Pediatric Dermatology - Wiley InterScience

Psoriasis, Guttate: eMedicine Dermatology

2010-01-23T23:25:00.000-08:00

Psoriasis, Guttate: eMedicine Dermatology

Guttate psoriasis primarily occurs on the trunk and the proximal extremities, but it may have a generalized distribution. New guttate psoriasis lesions develop during the first month of disease, they remain stable during the second month, and the remission begins during the third month.1 The word guttate is derived from the Latin word gutta, meaning drop.

Guttate psoriasis is more common in individuals younger than 30 years, and a history of upper respiratory tract infection secondary to group A beta-hemolytic streptococci (eg, Streptococcus pyogenes) often precedes the eruption by 2-3 weeks.2 Streptococcal perianal dermatitis, a superficial bacterial infection of the anus and perianal skin in children, has also been linked with the appearance of guttate psoriasis.3,4 Although episodes may recur, especially those due to pharyngeal carriage of streptococci, isolated bouts have also been described. The sudden appearance of the papular lesions in response to streptococcal infection may be either the first manifestation of psoriasis in a previously unaffected individual or an acute exacerbation of long-standing plaque psoriasis. Uncommonly, guttate psoriasis may be chronic in nature and/or arise in the absence of preceding streptococcal infection.

A double-blind evaluation of topical capsaicin in ...[J Am Acad Dermatol. 1993] - PubMed Result

2009-09-05T20:56:00.001-07:00

A double-blind evaluation of topical capsaicin in ...[J Am Acad Dermatol. 1993] - PubMed Result

Effects of topically applied capsaicin on moderate...[J Am Acad Dermatol. 1986] - PubMed Result

2009-09-05T20:56:00.000-07:00

Effects of topically applied capsaicin on moderate to severe psoriasis vulgaris [J Am Acad Dermatol. 1986] - PubMed Result

Unbound MEDLINE | TARS. Their role in the treatment of psoriasis. Journal article

2009-09-01T19:38:00.000-07:00

Unbound MEDLINE TARS. Their role in the treatment of psoriasis. Journal article

Unbound MEDLINE | Coal tar phototherapy for psoriasis reevaluated: erythemogenic versus suberythemogenic ultraviolet with a tar extract in oil and crude coal tar. Journal article

2009-09-01T19:36:00.000-07:00

Unbound MEDLINE Coal tar phototherapy for psoriasis reevaluated: erythemogenic versus suberythemogenic ultraviolet with a tar extract in oil and crude coal tar. Journal article

A Study to Evaluate the Safety and Effectiveness of Doxercalciferol Capsules in Patients With Moderate to Severe Psoriasis - Full Text View - ClinicalTrials.gov

2009-09-01T19:27:00.000-07:00

A Study to Evaluate the Safety and Effectiveness of Doxercalciferol Capsules in Patients With Moderate to Severe Psoriasis - Full Text View - ClinicalTrials.gov

Topical tar: back to the future. [J Am Acad Dermatol. 2009] - PubMed Result

2009-09-01T19:15:00.000-07:00

Topical tar: back to the future. [J Am Acad Dermatol. 2009] - PubMed Result

Paghdal KV, Schwartz RA.
Dermatology and Pathology, New Jersey Medical School, Newark, New Jersey 07103, USA.

The use of medicinal tar for dermatologic disorders dates back to the ancient times. Although coal tar is utilized more frequently in modern dermatology, wood tars have also been widely employed. Tar is used mainly in the treatment of chronic stable plaque psoriasis, scalp psoriasis, atopic dermatitis, and seborrheic dermatitis, either alone or in combination therapy with other medications, phototherapy, or both. Many modifications have been made to tar preparations to increase their acceptability, as some dislike its odor, messy application, and staining of clothing. One should consider a tried and true treatment with tar that has led to clearing of lesions and prolonged remission times. Occupational studies have demonstrated the carcinogenicity of tar; however, epidemiologic studies do not confirm similar outcomes when used topically. This article will review the pharmacology, formulations, efficacy, and adverse effects of crude coal tar and other tars in the treatment of selected dermatologic conditions.

Malabsorption: eMedicine Gastroenterology

2009-08-03T21:42:00.000-07:00

Malabsorption: eMedicine Gastroenterology

Skin basement membrane zone: a depository for circ...[Skinmed. 2006 Mar-Apr] - PubMed Result

2009-08-03T21:22:00.000-07:00

Skin basement membrane zone: a depository for circ...[Skinmed. 2006 Mar-Apr] - PubMed Result

The Journal of Antibiotics - Abstract of article: Identification of Macrolide Antibiotic-binding Human_p8 Protein

2009-08-03T21:20:00.000-07:00

The Journal of Antibiotics - Abstract of article: Identification of Macrolide Antibiotic-binding Human_p8 Protein

A new approach for containment of microorganisms: Dual control of streptavidin expression by antisense RNA and the T7 transcriptionsystem

2009-08-03T21:18:00.000-07:00

A new approach for containment of microorganisms: Dual control of streptavidin expression by antisense RNA and the T7 transcription<img src="corehtml/pmc/pmcents/x2009.gif" border="0" alt=" " title=""/>system

Skin basement membrane zone: a depository for circulating microbial antigen [Skinmed. 2006 Mar-Apr] - PubMed Result

2009-08-01T22:37:00.000-07:00

Skin basement membrane zone: a depository for circulating microbial antigen
evoking psoriasis and autoimmunity.[Skinmed. 2006 Mar-Apr] - PubMed Result

Noah PW, Handorf CR, Skinner RB Jr, Mandrell TD, Rosenberg EW.
Department of Medicine (Dermatology) and Preventive Medicine, University of Tennessee, Memphis, TN 38104-7514, USA.

BACKGROUND: Elevated levels of antibody to streptococcal exoenzymes have been found in patients with psoriasis or psoriatic arthritis. Research on the role of streptococcal antigen in psoriasis has been hampered by a potential molecular mimicry between streptococcal epitopes and human epidermal keratin. OBJECTIVE AND METHODS: Evidence of microbial product was sought in skin biopsies of psoriasis patients thought clinically to have either streptococcal carrier state or gastrointestinal candidal colonization. A polyclonal antibody to streptococcal-derived exoenzymes unlikely to share antigenic structures with normal human skin, and an anticandidal antibody, were used with linked streptavidin biotin amplification stain. RESULTS: The predicted microbial product appeared heavily in lesional epidermis, but unexpectedly also as a thin deposit along the skin basement membrane zone (SBMZ) of apparently unaffected skin. Staining was negative for nonpsoriatic subjects. CONCLUSIONS: The findings support a direct effect of microbial antigen in psoriasis. They also suggest an important role for SBMZ as a very large adhesive surface in the first step of a process of percutaneous epidermal elimination of foreign antigens and microbial toxins. The many autoimmune phenomena seen so often at the SBMZ are probably a physiologic part of this important immune function. Efforts to enhance the adhesive properties of SBMZ should be exploitable for both diagnostic and therapeutic benefit.